BDBM50430241 CHEMBL2332488

SMILES CN(C)CCCn1c2ccccc2c(-c2ccccc2)c(C#N)c1=O

InChI Key InChIKey=RQAGIIPBHMAHTO-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50430241   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50430241(CHEMBL2332488)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as calcium ion influx by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50430241(CHEMBL2332488)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50430241(CHEMBL2332488)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of 5HT3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50430241(CHEMBL2332488)
Affinity DataEC50:  8.20E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as area under the curve of acetylcholine-induced response by whole-cell patch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed