BDBM50433761 CHEMBL2381601

SMILES N[C@H]1CC[C@@H](CC1)Nc1ncc(C(N)=O)n2cc(nc12)-c1ccc(Cl)cc1

InChI Key InChIKey=DIVVQJIIRBQSMU-HDJSIYSDSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50433761   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human CAMK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTestis-specific serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human TSSK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human CSNK1DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human IKKBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433761(CHEMBL2381601)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed