BDBM50434133 CHEMBL2381643
SMILES N[C@]1(C[C@H](O)[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O
InChI Key InChIKey=XMDLTKGXRPVDSY-FJNNMDBYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50434133
Affinity DataKi: 230nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human mGlu8 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Agonist activity at mGlu3 (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataEC50: 6.60nMAssay Description:Agonist activity at human mGlu3 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Agonist activity at mGlu2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 7.5nMAssay Description:Agonist activity at human mGlu2 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.04E+3nMAssay Description:Antagonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 assessed as inhibition of forskolin-stim...More data for this Ligand-Target Pair