BDBM50434364 CHEMBL2386764::US9446044, 65

SMILES COC(=N)c1nc2ccc3ncnc(Nc4ccc(C)cc4)c3c2s1

InChI Key InChIKey=AVKKQBJQERVCTD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434364   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of recombinant DYRK1A (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed