BDBM50434451 CHEMBL2385124
SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(O)=O
InChI Key InChIKey=GHYFLKZMAHTBNE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50434451
Affinity DataIC50: 14nMAssay Description:Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding preinc...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CRTh2 receptor in human eosinophil assessed as inhibition of PGD2-induced cell shape changeMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of PGD2-induced eosinophil shape changeMore data for this Ligand-Target Pair