BDBM50435344 CHEMBL2391541
SMILES COc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1
InChI Key InChIKey=HGRHWEAUHXYNNP-UHFFFAOYSA-N
Data 55 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 55 hits for monomerid = 50435344
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Binding affinity to 5-HT 1A (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to 5-HT 1A (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Binding affinity to 5-HT 2B (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Binding affinity to 5-HT 7 (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Binding affinity to 5-HT 1D (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Binding affinity to 5-HT 1D (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 155nMAssay Description:Binding affinity to 5-HT 6 (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 214nMAssay Description:Binding affinity to alpha-2A adrenergic receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 218nMAssay Description:Binding affinity to 5-HT 2A (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 219nMAssay Description:Binding affinity to 5-HT 2A (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 302nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Ucl School Of Pharmacy
Curated by ChEMBL
Ucl School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 398nMAssay Description:Displacement of [3H]Pentazocine from guinea pig sigma 1 receptor after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Ucl School Of Pharmacy
Curated by ChEMBL
Ucl School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Displacement of [3H]Pentazocine from guinea pig sigma 1 receptor after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 457nMAssay Description:Binding affinity to 5-HT 2C (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 501nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 501nMAssay Description:Binding affinity to SERT (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 501nMAssay Description:Binding affinity to 5-HT 1E (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 724nMAssay Description:Binding affinity to alpha-2B adrenergic receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 741nMAssay Description:Binding affinity to 5-HT 1B (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 936nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting an...More data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 936nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting an...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 1.12E+3nMAssay Description:Binding affinity to kappa type opioid receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 1.48E+3nMAssay Description:Binding affinity to alpha-2C adrenergic receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Binding affinity to histamine H3 receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 3.16E+3nMAssay Description:Binding affinity to DAT (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: 3.31E+3nMAssay Description:Binding affinity to 5-HT 5A (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.25E+3nMAssay Description:Displacement of [3H]Tiotidine from human recombinant histamine H2 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting ana...More data for this Ligand-Target Pair
Affinity DataKi: 4.27E+3nMAssay Description:Displacement of [3H]Tiotidine from human recombinant histamine H2 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting ana...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to kappa type opioid receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to alpha-1D adrenergic receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to alpha-1A adrenergic receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to mu type opioid receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to NET (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to alpha-2C adrenergic receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to D2 dopamine receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5-HT 2A (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human recombinant dopamine D2 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation count...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Ucl School Of Pharmacy
Curated by ChEMBL
Ucl School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha4beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Ucl School Of Pharmacy
Curated by ChEMBL
Ucl School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from alpha4beta2 nACh receptor in HEK293 cells after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Ucl School Of Pharmacy
Curated by ChEMBL
Ucl School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha4beta2 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
Ucl School Of Pharmacy
Curated by ChEMBL
Ucl School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha2beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2(Homo sapiens (Human))
Ucl School Of Pharmacy
Curated by ChEMBL
Ucl School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha2beta2 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5-HT 1A (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5-HT 1D (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LY278584 from human recombinant 5-HT3 receptor expressed in HEK293T cells after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5-HT 2C (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to alpha-2B adrenergic receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to D3 dopamine receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
The Alexander Shulgin Research Institute
Curated by ChEMBL
The Alexander Shulgin Research Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin) by competition binding assayMore data for this Ligand-Target Pair