BDBM50435668 CHEMBL2391800

SMILES O[C@H](COc1cc(F)ccc1C(=O)N1CC[C@H](O)C1)CN1CCC2(Cc3cc(Cl)ccc3O2)CC1

InChI Key InChIKey=QUWJHBYTQZGSSF-SFTDATJTSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435668   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50435668(CHEMBL2391800)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage inflammatory protein-1 alpha receptor(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50435668(CHEMBL2391800)
Affinity DataIC50:  2.50E+3nMAssay Description:Antagonist activity at rat CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed