BDBM50435676 CHEMBL2391938

SMILES COc1ccc(C(=O)NC2CC2)c(OC[C@@H](O)CN2CCC3(Cc4cc(Cl)ccc4O3)CC2)c1

InChI Key InChIKey=MVACDKPCOURBQW-FQEVSTJZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435676   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50435676(CHEMBL2391938)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage inflammatory protein-1 alpha receptor(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50435676(CHEMBL2391938)
Affinity DataIC50:  79nMAssay Description:Antagonist activity at rat CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed