BDBM50435684 CHEMBL2391794

SMILES CNC(=O)c1ccc(O)cc1OC[C@@H](O)CN1CCC2(Cc3cc(F)ccc3O2)CC1

InChI Key InChIKey=KZJPBYOFBQXPKM-SFHVURJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435684   

TargetMacrophage inflammatory protein-1 alpha receptor(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50435684(CHEMBL2391794)
Affinity DataIC50:  890nMAssay Description:Antagonist activity at rat CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50435684(CHEMBL2391794)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed