BDBM50436151 CHEMBL2398212

SMILES Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N

InChI Key InChIKey=BIGPXXAUSQLTQR-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50436151   

TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50:  420nMAssay Description:Inhibition of USP7 (unknown origin) using ubiquitin-EKL as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50:  96nMAssay Description:Inhibition of human full-length His-tagged USP8 expressed baculovirus infected insect cells using Ub-AMC as substrate by fluorescence spectroscopic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50:  420nMAssay Description:Inhibition of full length wild-type human N-terminal His-tagged USP7 expressed in baculovirus infected Sf9 cells using Ub-AMC as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50:  960nMAssay Description:Inhibition of USP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50:  400nMAssay Description:Inhibition of human USP7 using Ub-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 47(Homo sapiens (Human))TBA
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50:  400nMAssay Description:Inhibition of USP47 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50:  96nMAssay Description:Inhibition of human USP8 using Ub-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50436151(CHEMBL2398212)
Affinity DataIC50:  424nMAssay Description:Inhibition of human USP7More data for this Ligand-Target Pair
In DepthDetails PubMed