BDBM50436200 CHEMBL282489

SMILES CC[C@@H]1Cc2cc(O)ccc2C2=C1c1ccc(O)cc1C[C@H]2CC

InChI Key InChIKey=MASYAWHPJCQLSW-ZIAGYGMSSA-N

Data  1 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436200   

TargetBile acid receptor(Homo sapiens (Human))
City Of Hope National Medical Center

Curated by ChEMBL
LigandPNGBDBM50436200(CHEMBL282489)
Affinity DataIC50:  1.31E+3nMAssay Description:Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
City Of Hope National Medical Center

Curated by ChEMBL
LigandPNGBDBM50436200(CHEMBL282489)
Affinity DataEC50:  8.60E+3nMAssay Description:Agonist activity at PXR (unknown origin) expressed in human HepG2 cells assessed as induction of CYP3A4 transactivation after 16 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed