BDBM50436476 CHEMBL2397316

SMILES Cc1nc(NC(=O)C(C)(C)CC(F)(F)F)sc1-c1ccc(N)nc1

InChI Key InChIKey=UGTHQAXCCBBNQW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50436476   

TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50436476(CHEMBL2397316)
Affinity DataIC50:  48nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50436476(CHEMBL2397316)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17A(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50436476(CHEMBL2397316)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of STK17A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50436476(CHEMBL2397316)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of PIK3C2B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50436476(CHEMBL2397316)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of PIK3C2A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50436476(CHEMBL2397316)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of MSK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed