BDBM50436541 CHEMBL2396663
SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C
InChI Key InChIKey=PWZPBZQTTHOCIS-HHHXNRCGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50436541
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]spiperone from human dopamine D2S receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in porcine striatal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galpha0i assessed as [35S]GTPgammaS binding after 30 ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMAssay Description:Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 ...More data for this Ligand-Target Pair
Affinity DataEC50: 92nMAssay Description:Intrinsic activity at human dopamine D2L receptor expressed in HEK293 cells co-transfected with Galpha0i assessed as [35S]GTPgammaS binding after 30 ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Intrinsic activity at human dopamine D2L receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 ...More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at ARMS2-PK2-tagged human dopamine D2S receptor expressed in HEK293 cells co-expressing (EA)-tagged beta arrestin fusion protein ass...More data for this Ligand-Target Pair