BDBM50436542 CHEMBL2397389
SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C
InChI Key InChIKey=PWZPBZQTTHOCIS-MHZLTWQESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50436542
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.80nMAssay Description:Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]spiperone from human dopamine D2S receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in porcine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 2.80E+4nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at ARMS2-PK2-tagged human dopamine D2S receptor expressed in HEK293 cells co-expressing (EA)-tagged beta arrestin fusion protein ass...More data for this Ligand-Target Pair
Affinity DataEC50: 66nMAssay Description:Intrinsic activity at human dopamine D2L receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 ...More data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Intrinsic activity at human dopamine D2L receptor expressed in HEK293 cells co-transfected with Galpha0i assessed as [35S]GTPgammaS binding after 30 ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 ...More data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galpha0i assessed as [35S]GTPgammaS binding after 30 ...More data for this Ligand-Target Pair