BDBM50436648 CHEMBL2398286

SMILES CC(N=Nc1nc2ccccc2s1)c1cccc(c1)-c1cccc(n1)C(O)=O

InChI Key InChIKey=FYHVBVFEIYSUTF-UHFFFAOYSA-N

Data  4 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50436648   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL
LigandPNGBDBM50436648(CHEMBL2398286)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL
LigandPNGBDBM50436648(CHEMBL2398286)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL
LigandPNGBDBM50436648(CHEMBL2398286)
Affinity DataKd:  61nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl assessed as direct binding constant at steady state by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL
LigandPNGBDBM50436648(CHEMBL2398286)
Affinity DataIC50:  120nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL
LigandPNGBDBM50436648(CHEMBL2398286)
Affinity DataKd:  79nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl assessed as dissociation rate by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL
LigandPNGBDBM50436648(CHEMBL2398286)
Affinity DataIC50:  140nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed