BDBM50437157 CHEMBL2401814
SMILES C[C@H](Oc1c(N)ncc2c(coc12)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl
InChI Key InChIKey=RFKWZWJQRQCLJF-LBPRGKRZSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50437157
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of cMET in human MKN45 cells assessed as phosphorylated MET levels after 4 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibition of cMET (unknown origin) using biotinylated poly(Glu,Tyr) as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of cMET (unknown origin) using biotinylated poly(Glu,Tyr) as substrate after 60 minsMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of short-form RON (unknown origin) expressed in human HeLa cells assessed as phosphorylated RON levels after 4 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of cMET in human MKN45 cells assessed as phosphorylated MET levels after 4 hrsMore data for this Ligand-Target Pair