BDBM50437694 CHEMBL1410015

SMILES Cc1cc(C(=O)CN2CCCC2)c(C)n1-c1ccc(F)cc1

InChI Key InChIKey=JUWDSDKJBMFLHE-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50437694   

TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Tokyo University Of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437694(CHEMBL1410015)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human USP14More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Tokyo University Of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437694(CHEMBL1410015)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of USP14 (unknown origin) by Ub-AMC assayMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50437694(CHEMBL1410015)
Affinity DataIC50:  1.43E+5nMAssay Description:Inhibition of human USP5 using Ub-PA as substrate assessed as deubiquitination level incubated for 1 hr by SDS-PAGE assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Tokyo University Of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437694(CHEMBL1410015)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of human USP14 using Ub-PA as substrate assessed as deubiquitination level incubated for 1 hr by SDS-PAGE assayMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Tokyo University Of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437694(CHEMBL1410015)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of full-length human USP14 using Ub-AMC substrateMore data for this Ligand-Target Pair