BDBM50437695 CHEMBL1923233

SMILES CCC[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1

InChI Key InChIKey=LIDOPKHSVQTSJY-VMEIHUARSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50437695   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Tokyo University Of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437695(CHEMBL1923233)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of UCH-L1 in human Z138 cells after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable ubiquitin carboxyl-terminal hydrolase FAF-X(Homo sapiens (Human))
Tokyo University Of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437695(CHEMBL1923233)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of USP9x in human Z138 cells after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable ubiquitin carboxyl-terminal hydrolase FAF-X(Homo sapiens (Human))
Tokyo University Of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437695(CHEMBL1923233)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of USP9x (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable ubiquitin carboxyl-terminal hydrolase FAF-X(Homo sapiens (Human))
Tokyo University Of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437695(CHEMBL1923233)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human recombinant N-terminal His6-Smt3-fusion-tagged Usp9x catalytic domain expressed in Escherichia coli using Ub-AMC as substrate inc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 5(Homo sapiens (Human))
Tokyo University Of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437695(CHEMBL1923233)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of USP5 in human Z138 cells after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed