BDBM50438537 CHEMBL2414861

SMILES O=[#6](-[#7]\[#7]=[#6](\c1ccccc1)-c1ccccc1)-[#7]-c1ccncc1

InChI Key InChIKey=GYGIBXHJGSWTKF-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50438537   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50438537(CHEMBL2414861)
Affinity DataKi:  82nMAssay Description:Non competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50438537(CHEMBL2414861)
Affinity DataKi:  1.68E+4nMAssay Description:Competitive inhibition of human serum BChE using butyrylthiocholine iodide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50438537(CHEMBL2414861)
Affinity DataIC50:  52nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50438537(CHEMBL2414861)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed