BDBM50439464 CHEMBL2420909

SMILES C1CCC2(CCN(CC2)c2ncnc3nc[nH]c23)NC1

InChI Key InChIKey=SLPPJSSITOXUMX-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50439464   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  1.26E+5nMAssay Description:Inhibition of ABL (unknown origin) by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of RSK1 (unknown origin) by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of MSK1 (unknown origin) by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of AKT1 (unknown origin) by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of CHK1 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  2.38E+5nMAssay Description:Inhibition of CK1delta (unknown origin) by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of CHK2 (unknown origin) by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of PKD2 (unknown origin) by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  2.26E+5nMAssay Description:Inhibition of PRAK (unknown origin) by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of AURA (unknown origin) by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50439464(CHEMBL2420909)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of ERK2 (unknown origin) by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed