BDBM50439675 CHEMBL2417788::US11279687, Compound 196

SMILES FC(F)(F)Oc1ccccc1S(=O)(=O)c1ccc(NC(=O)NCc2cccnc2)cc1

InChI Key InChIKey=ZBHIXLLQTRBMHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439675   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50439675(CHEMBL2417788 | US11279687, Compound 196)
Affinity DataIC50:  1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM50439675(CHEMBL2417788 | US11279687, Compound 196)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed