BDBM50439807 CHEMBL2419718::US9227982, 4
SMILES Fc1ccccc1CCC(=O)N(Cc1cccs1)Cc1nc2CCOCc2c(=O)[nH]1
InChI Key InChIKey=HVPUASJORDGFQX-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50439807
Affinity DataIC50: 64nMT: 2°CAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 304nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
Affinity DataIC50: 271nMT: 2°CAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair