BDBM50440033 CROMOLYN::Crolom::Cromoglicic Acid

SMILES OC(COc1cccc2oc(cc(=O)c12)C(O)=O)COc1cccc2oc(cc(=O)c12)C(O)=O

InChI Key InChIKey=IMZMKUWMOSJXDT-UHFFFAOYSA-N

Data  2 KI  3 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50440033   

TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataKi:  2.34E+3nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataKi:  2.97E+3nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human GPR35 by Ca+2 release assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataEC50:  520nMAssay Description:Agonist activity at human GPR35 by DMR assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataEC50:  7.00E+3nMAssay Description:Agonist activity at GPR-35 (unknown origin) by beta-arrestin assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataEC50:  7.00E+3nMAssay Description:Agonist activity at human GPR35 expressed in CHO-K1 cells after 90 mins by beta-arrestin 2 recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataEC50:  52nMAssay Description:Agonist activity at human GPR35 expressed in CHO-K1 cells by DMR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataEC50:  520nMAssay Description:Agonist activity at GPR-35 (unknown origin) expressed in HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50440033(CROMOLYN | Crolom | Cromoglicic Acid)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed