BDBM50440106 CHEMBL2426113
SMILES CC(C)C[C@@H](c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(C)(C)CNC(=O)NC(C)(C)C
InChI Key InChIKey=USDRMZNMCWLDGV-QHCPKHFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50440106
Affinity DataKi: 3.60nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Transrepression activity at glucocorticoid receptor in human A549 cells assessed as inhibition of PMA-stimulated AP1 response element by luciferase r...More data for this Ligand-Target Pair
Affinity DataEC50: 126nMAssay Description:Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Transrepression activity at glucocorticoid receptor in human A549 cells assessed as inhibition of IL1beta-stimulated NFkappaB-dependent E-selectin tr...More data for this Ligand-Target Pair