BDBM504404 2-((R)-3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)-4-(azetidin-1-yl)-4-methylpent-2-enenitrile bis (2,2,2-trifluoroacetate)::US11040980, Example 2

SMILES CC(C)(C=C(C#N)C(=O)N1CCC[C@H](C1)N1C=[N](c2c1ncnc2N)c1ccc(Oc2ccccc2)cc1F)N1CCC1

InChI Key InChIKey=PYWOBJUHXMCRER-HSZRJFAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504404   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM504404(2-((R)-3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-...)
Affinity DataIC50:  4.10nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of the pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent