BDBM50441041 CHEMBL2430163::US9695176, 3

SMILES Cc1cc(CC(OC(=O)N2CCC(CC2)c2cc3ccccc3[nH]c2=O)c2ncc3CNCCn23)cc2cn[nH]c12

InChI Key InChIKey=STJBKZREPWJSHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441041   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50441041(CHEMBL2430163 | US9695176, 3)
Affinity DataIC50:  2.90nMAssay Description:Antagonist activity at human CGRP receptor expressed in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50441041(CHEMBL2430163 | US9695176, 3)
Affinity DataIC50:  2.95nMpH: 7.5 T: 2°CAssay Description:The compounds of invention were solubilized and carried through serial dilutions using 100% DMSO. Aliquots from the compound serial dilutions were fu...More data for this Ligand-Target Pair
In DepthDetails US Patent