BDBM50441042 CHEMBL2430164::US9695176, 2

SMILES CCN1CCn2c(C1)cnc2C(Cc1cc(C)c2[nH]ncc2c1)OC(=O)N1CCC(CC1)c1cc2ccccc2[nH]c1=O

InChI Key InChIKey=VEWKJXMBTJTFJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441042   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50441042(CHEMBL2430164 | US9695176, 2)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human CGRP receptor expressed in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50441042(CHEMBL2430164 | US9695176, 2)
Affinity DataIC50:  1.70nMpH: 7.5 T: 2°CAssay Description:The compounds of invention were solubilized and carried through serial dilutions using 100% DMSO. Aliquots from the compound serial dilutions were fu...More data for this Ligand-Target Pair
In DepthDetails US Patent