BDBM50441090 CHEMBL2430323::US9669028, 114 N-(3-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl)acetamide
SMILES CC(=O)Nc1cccc(c1)-c1cnc2[nH]nc(C)c2c1
InChI Key InChIKey=YFBPGSDPFRCNOY-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50441090
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Arrien Pharmaceuticals
US Patent
Arrien Pharmaceuticals
US Patent
Affinity DataIC50: >1.00E+3nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Arrien Pharmaceuticals
US Patent
Arrien Pharmaceuticals
US Patent
Affinity DataIC50: >1.00E+3nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Edinburgh Cancer Research Centre In The Institute Of Genetics And Molecular Medicine
Curated by ChEMBL
University Of Edinburgh Cancer Research Centre In The Institute Of Genetics And Molecular Medicine
Curated by ChEMBL
Affinity DataIC50: 233nMAssay Description:Inhibition of human CHK1 in presence of 20 uM ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 15(Homo sapiens (Human))
University Of Edinburgh Cancer Research Centre In The Institute Of Genetics And Molecular Medicine
Curated by ChEMBL
University Of Edinburgh Cancer Research Centre In The Institute Of Genetics And Molecular Medicine
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human ERK8 in presence of 5 uM ATPMore data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
University Of Edinburgh Cancer Research Centre In The Institute Of Genetics And Molecular Medicine
Curated by ChEMBL
University Of Edinburgh Cancer Research Centre In The Institute Of Genetics And Molecular Medicine
Curated by ChEMBL
Affinity DataIC50: 894nMAssay Description:Inhibition of rat CK1delta in presence of 20 uM ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
University Of Edinburgh Cancer Research Centre In The Institute Of Genetics And Molecular Medicine
Curated by ChEMBL
University Of Edinburgh Cancer Research Centre In The Institute Of Genetics And Molecular Medicine
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human NEK2alpha in presence of 50 uM ATPMore data for this Ligand-Target Pair