BDBM50443025 CHEMBL3087638
SMILES N[C@@H](CCCN(CCI)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O
InChI Key InChIKey=RJVFQYHZKQOEQT-UOYPZJKHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50443025
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Competitive inhibition of recombinant human DOT1L using adenosine/deazaadenosine as substrate and SAM cofactorMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human DOT1L (1 to 472) using [3H]-SAM/oligo-nucleosome as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair