BDBM50443132 CHEMBL3086175::US9221797, 42
SMILES O=C(Nc1ccc(CCN2CCOCC2)cc1C1=CCCCC1)c1ncc([nH]1)C#N
InChI Key InChIKey=UURBEBBVEFUFRK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50443132
TargetMacrophage colony-stimulating factor 1 receptor [555-568](Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 1.43nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure
compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic
CS...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Research And Development
Curated by ChEMBL
Janssen Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FMS in mouse BMDM cellsMore data for this Ligand-Target Pair