BDBM50443155 CHEMBL3085972::US8674100, 145

SMILES CC(C)(CN1CCS(=O)(=O)CC1)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1

InChI Key InChIKey=SREKLVZBGOOWFZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443155   

TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443155(CHEMBL3085972 | US8674100, 145)
Affinity DataIC50:  3.5nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443155(CHEMBL3085972 | US8674100, 145)
Affinity DataIC50:  19nMAssay Description:Inhibition of FMS in mouse BMDM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50443155(CHEMBL3085972 | US8674100, 145)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed