BDBM50443391 CHEMBL469695
SMILES Fc1ccc(CNC(=O)N2CCN3C(C2)C(OC3=O)(c2ccccc2)c2ccccc2)cc1
InChI Key InChIKey=SFRQIPRTNYHJHP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50443391
Affinity DataKi: 48nMAssay Description:Binding affinity to human NPSR by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Displacement of [125I]Tyr10-NPS from neuropeptide S receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]Tyr10-NPS from human neuropeptide S receptor expressed in CHO cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair