BDBM50446370 CHEMBL3109598

SMILES COc1ccc(NC(c2c(C)[nH]c3ccccc23)c2ccc(cc2)C(F)(F)F)cc1OC

InChI Key InChIKey=ZLBSKWHEUQSLOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446370   

TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50446370(CHEMBL3109598)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD (unknown origin)-SRC2-3 interaction after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50446370(CHEMBL3109598)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of 1,25(OH)2D3-induced VDR (unknown origin)-mediated CYP24A1 transcription expressed in HEK293T cells after 16 hrs by luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed