BDBM50446585 CHEMBL3116440

SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(O)n(-c4ccc(C)cc4)c(=O)[nH]c3=O)ccnc2cc1OCCCN1CCCC1

InChI Key InChIKey=KAPOJQHBFXHFOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50446585   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50446585(CHEMBL3116440)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50446585(CHEMBL3116440)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50446585(CHEMBL3116440)
Affinity DataIC50:  496nMAssay Description:Inhibition of Flt-3 (unknown origin) using poly (Glu, Tyr) 4:1 after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed