BDBM50446953 CHEMBL3115774

SMILES CCCCCCc1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O

InChI Key InChIKey=HIVUMAXJGBETMO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50446953   

TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Florida Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50446953(CHEMBL3115774)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at 5-oxo-ETE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced Ca2+ mobilization incubated for 2 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Florida Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50446953(CHEMBL3115774)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Florida Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50446953(CHEMBL3115774)
Affinity DataIC50:  402nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in neutrophils assessed as inhibition of 5-oxo-ETE-induced cell migration after 2 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Florida Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50446953(CHEMBL3115774)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Florida Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50446953(CHEMBL3115774)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Florida Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50446953(CHEMBL3115774)
Affinity DataIC50:  2.18E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Florida Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50446953(CHEMBL3115774)
Affinity DataIC50:  2.17E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxoeicosanoid receptor 1(Homo sapiens (Human))
Florida Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50446953(CHEMBL3115774)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in anti-CD49d-labeled eosinophils assessed as inhibition of 5-oxo-ETE-induced F-actin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed