BDBM50447577 CHEMBL1494030

SMILES Cn1nccc1C(=O)Nc1cccnc1

InChI Key InChIKey=LSEUGEFZKAZGSI-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447577   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50447577(CHEMBL1494030)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of full length C-terminal His6-tagged human NAMPT expressed in Escherichia coli Rosetta (DE3) cells using PRPP/NAM as substrate/cofactor p...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50447577(CHEMBL1494030)
Affinity DataKd:  5.20E+3nMAssay Description:Binding affinity to N-terminal His6-tagged/biotinylated C-terminal Avi-tagged human NAMPT (2 to 491) by SPR analysisMore data for this Ligand-Target Pair