BDBM50447868 CHEMBL3114776

SMILES CN(CCOc1cccc(NC2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c1)c1ccnc(F)c1

InChI Key InChIKey=SKJAPOHPBVKPHD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50447868   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447868(CHEMBL3114776)
Affinity DataIC50:  46nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447868(CHEMBL3114776)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447868(CHEMBL3114776)
Affinity DataIC50:  490nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed