BDBM50447878 CHEMBL3114766

SMILES O=C1NC(=O)C(=C1Nc1cccc(OCCCn2ccnc2)c1)c1c[nH]c2ccccc12

InChI Key InChIKey=PCRCFPMHQKVAMW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50447878   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447878(CHEMBL3114766)
Affinity DataIC50:  128nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447878(CHEMBL3114766)
Affinity DataIC50:  300nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447878(CHEMBL3114766)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed