BDBM50447883 CHEMBL3114761

SMILES Fc1cc(ccn1)N1CC[C@@H](C1)Oc1cccc(NC2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c1

InChI Key InChIKey=ULLVSXLCIMTNQM-IBGZPJMESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50447883   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447883(CHEMBL3114761)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447883(CHEMBL3114761)
Affinity DataIC50:  13nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447883(CHEMBL3114761)
Affinity DataIC50:  628nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed