BDBM50447934 CHEMBL3114982

SMILES Cc1cc(=O)n([nH]1)-c1nc2ccccc2[nH]1

InChI Key InChIKey=RRXNULSELUJDDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447934   

TargetLysine-specific demethylase 4E(Homo sapiens (Human))
Max Delbr�Ck Center For Molecular Medicine In The Helmholtz Gemeinschaft (Mdc)

Curated by ChEMBL
LigandPNGBDBM50447934(CHEMBL3114982)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Homo sapiens (Human))
Hyogo University Of Health Science

Curated by ChEMBL
LigandPNGBDBM50447934(CHEMBL3114982)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed