BDBM504493 2-{5-[(3-Ethoxy-5-fluoropyridin-2-yl)oxy]pyridin-3-yl}-N-[(3R,4R)-4-fluoropiperidin-3-yl]pyrimidine-5-carboxamide ::US11065249, Example 6::US11471458, Example 6::US20230405002, Example 6
SMILES CCOc1cc(F)cnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)N[C@@H]1CNCC[C@H]1F
InChI Key InChIKey=XZBQFIHUGFHQGB-QZTJIDSGSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 504493
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Smith, Gambrell & Russell
Curated by ChEMBL
Smith, Gambrell & Russell
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of DGAT2 in human hepatocytes using [14C]-glycerol as substrate preincubated for 15 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair