BDBM504500 2-{5-[(3-ethoxy-5-fluoropyridin-2- yl)oxy]pyridin-3-yl}-N-[(3S,4S)-4- fluoropiperidin-3-yl]pyrimidine-5- carboxamide, formate salt::US11065249, Example 13::US20230405002, Example 13
SMILES CCOc1cc(F)cnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)N[C@H]1CNCC[C@@H]1F
InChI Key InChIKey=XZBQFIHUGFHQGB-ROUUACIJSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 504500
Affinity DataIC50: 57nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of DGAT2 in human hepatocytes using [14C]-glycerol as substrate preincubated for 15 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair