BDBM50450263 CHEMBL4176503

SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O

InChI Key InChIKey=RZAMDGBOOPJHJQ-GHTZIAJQSA-N

Data  1 KI  4 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50450263   

TargetFree fatty acid receptor 2(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50450263(CHEMBL4176503)
Affinity DataKi:  204nMAssay Description:Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50450263(CHEMBL4176503)
Affinity DataEC50:  794nMAssay Description:Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Mus musculus)
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50450263(CHEMBL4176503)
Affinity DataEC50:  5.01E+3nMAssay Description:Agonist activity at FFA2R in mouse mature adipocytes assessed as inhibition of isoproterenol-induced glycerol productionMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50450263(CHEMBL4176503)
Affinity DataEC50:  78nMAssay Description:Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Mus musculus)
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50450263(CHEMBL4176503)
Affinity DataEC50:  363nMAssay Description:Agonist activity at mouse FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...More data for this Ligand-Target Pair