BDBM50450626 CHEMBL4162723
SMILES CCOC(=O)c1cnn(c1C(F)(F)F)-c1ccc(cc1)-n1cc(nn1)-c1cccc(c1)C(O)=O
InChI Key InChIKey=ZGWMHBNCDPRDCJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50450626
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of STIM1/STIM2/Orai1 (unknown origin) expressed in mouse BV2 cells assessed as induction of store-operated calcium entry by measuring resi...More data for this Ligand-Target Pair
TargetCalcium release-activated calcium channel protein 1/Short transient receptor potential channel 1/Short transient receptor potential channel 3/Stromal interaction molecule 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...More data for this Ligand-Target Pair