BDBM50452393 CHEMBL4212760
SMILES CC(C)[C@@H]1N=C(c2ccccc2F)c2cc(Cl)ccc2NC1=S
InChI Key InChIKey=IIYOCBNZOLLZCM-INIZCTEOSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50452393
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Positive allosteric modulation of human wild type M1 receptor assessed as increase in acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataEC50: 178nMAssay Description:Positive allosteric modulation of M1 receptor Y179A/W400A mutant (unknown origin)More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Positive allosteric modulation of M5 receptor (unknown origin)More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataEC50: 218nMAssay Description:Positive allosteric modulation of rat M1 receptor assessed as increase in acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair