BDBM50452518 CHEMBL4204453

SMILES COc1cc2ccc3cc2cc1CCCCC(C)(C)COC(=O)N[C@H](C(=O)N1C[C@]3(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1)OC)C(C)(C)C

InChI Key InChIKey=PMPJBRQKPSKWGJ-JLOFFHGFSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452518   

TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452518(CHEMBL4204453)
Affinity DataEC50:  2.20nMAssay Description:Inhibition of HCV genotype 1a H77 NS3 protease infected in human HuH7 replicon cells assessed as reduction in viral replication after 4 days by lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452518(CHEMBL4204453)
Affinity DataEC50:  1.80nMAssay Description:Inhibition of HCV genotype 1b Con1 NS3 protease infected in human HuH7 replicon cells assessed as reduction in viral replication after 4 days by luci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed