BDBM50453117 CHEMBL4211486
SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1nc2cc(F)c(cc2[nH]1)[C@H]1CC[C@@H](N1c1cc(F)c(N2CCC(CC2)c2ccccc2)c(F)c1)c1cc2[nH]c(nc2cc1F)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C
InChI Key InChIKey=JERMZHAAAFJEKM-JIJYKOJWSA-N
Data 10 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50453117
Affinity DataEC50: 0.00900nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 6a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00200nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00300nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 2b assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 0.135nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0580nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00400nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 3a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00200nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 5a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00800nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 2a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00400nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 4a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00600nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days by luciferase reporter gene assa...More data for this Ligand-Target Pair