BDBM50453125 CHEMBL4214826

SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)C2(CCCC2)NC(=O)CC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O

InChI Key InChIKey=ODSFZEXVNOIJHI-ILOBPARPSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50453125   

TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453125(CHEMBL4214826)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453125(CHEMBL4214826)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453125(CHEMBL4214826)
Affinity DataIC50:  43nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453125(CHEMBL4214826)
Affinity DataIC50:  100nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453125(CHEMBL4214826)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453125(CHEMBL4214826)
Affinity DataEC50:  108nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453125(CHEMBL4214826)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed