BDBM504534 US11040966, Example 3.1::[(2S,4S)-2-(5-Chloro-4-methyl-1H-benzoimidazol-2-yl)-4-methoxy-pyrrolidin-1-yl]-(5-methyl-2-[1,2,3]triazol-2-yl-phenyl)-methanone

SMILES CO[C@H]1C[C@H](N(C1)C(=O)c1cc(C)ccc1-n1nccn1)c1nc2c(C)c(Cl)ccc2[nH]1

InChI Key InChIKey=VHWGLBVUOHRYHN-YWZLYKJASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504534   

TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM504534(US11040966, Example 3.1 | [(2S,4S)-2-(5-Chloro-4-m...)
Affinity DataIC50:  69nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM504534(US11040966, Example 3.1 | [(2S,4S)-2-(5-Chloro-4-m...)
Affinity DataIC50:  102nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent