BDBM50454140 CHEMBL3314033

SMILES COc1ccc(cc1)C(N(C)C(=O)c1ccc(=O)[nH]c1)C(=O)Nc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=PIBUURJIMMZKSJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454140   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50454140(CHEMBL3314033)
Affinity DataIC50:  100nMAssay Description:Displacement of BODIPY-cholesterol from human His-tagged RORgammat after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50454140(CHEMBL3314033)
Affinity DataIC50:  270nMAssay Description:Inverse agonist activity at RORgammat in human Jurkat cells assessed as inhibition of transcriptional activity after overnight incubation by human IL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed